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Ergonovine
CAS Number 60-79-7

This medication increases uterine contractions resulting in decreased uterine bleeding. It is used to treat or prevent uterine bleeding. It has also been used to treat migraine headaches.

Ergonovineis part of a group of medicines called ergot alkaloids. It is used to treat or prevent excessive bleeding after child birth.

General

Synonyms: 9,20-didehydro-N-(alpha-(hydroxymethyl)ethyl)-6-m-ethylergoline-8-beta-carboxamide, ergoline-8-carboxamide, N-((S)-2-hydroxy-1-methylethyl)-lysergamide, ergoatetrine, ergobasine, ergoklinine, ergotocine, ergometrine, ermetrine, margonovine, neofemergen, secacornin, secometrin Use:

Molecular formula: C19H23N3O2
CAS No: 60-79-7
EINECS No: 200-485-0


Physical data

Appearance: solid
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Stability

Stable. Incompatible with strong oxidizing agents.

Toxicology

Toxic if swallowed, inhaled or absorbed through the skin. May cause reproductive damage.

Personal protection

Safety glasses, gloves, good ventilation.

It has a medical use in obstetrics to facilitate delivery of the placenta and to prevent bleeding after childbirth by causing smooth muscle tissue in the blood vessel walls to narrow, thereby reducing blood flow. It is usually combined with oxytocin (syntocinon) as syntometrine.

It can induce spasm of the coronary arteries.

This is sometimes used in the differential diagnosis of angina.
 

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